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Mouse myeloid lineage differentiation

Myeloid lineage differentiation from mouse blood. Sequenced by SMARTseq in 2016 by Olsson et al. 660 cells x 112815 features with 4 cell type labels

mus musculus Organism
660 × 116,918 Dimensions
117.4 MiB Size
log_cp10k Normalization

Description

Myeloid lineage differentiation from mouse blood. Sequenced by SMARTseq in 2016 by Olsson et al. 660 cells x 112815 features with 4 cell type labels

Preview

An AnnData object with n_obs × n_vars = 660 × 116,918 with slots:

Data structure

Name Description Type Data type Size
obs
cell_type Classification of the cell type based on its characteristics and function within the tissue or organism. vector category 660
size_factors The size factors created by the normalisation method, if any. vector float32 660
var
feature_name A human-readable name for the feature, usually a gene symbol. vector object 116918
hvg Whether or not the feature is considered to be a 'highly variable gene' vector bool 116918
hvg_score A ranking of the features by hvg. vector float64 116918
obsp
knn_connectivities K nearest neighbors connectivities matrix. sparsematrix float32 660 × 660
knn_distances K nearest neighbors distance matrix. sparsematrix float64 660 × 660
obsm
X_pca The resulting PCA embedding. densematrix float32 660 × 50
varm
pca_loadings The PCA loadings matrix. densematrix float64 116918 × 50
layers
counts Raw counts sparsematrix float32 660 × 116918
normalized Normalised expression values sparsematrix float32 660 × 116918
uns
dataset_description Long description of the dataset. atomic str 1
dataset_id A unique identifier for the dataset. This is different from the `obs.dataset_id` field, which is the identifier for the dataset from which the cell data is derived. atomic str 1
dataset_name A human-readable name for the dataset. atomic str 1
dataset_organism The organism of the sample in the dataset. atomic str 1
dataset_reference Bibtex reference of the paper in which the dataset was published. atomic str 1
dataset_summary Short description of the dataset. atomic str 1
dataset_url Link to the original source of the dataset. atomic str 1
knn Supplementary K nearest neighbors data. dict 3
normalization_id Which normalization was used atomic str 1
pca_variance The PCA variance objects. dict 2

Download & explore

The processed dataset lives on the OpenProblems public S3 bucket, which is world-readable. Download the file directly, or copy its S3 URI to fetch it with your tool of choice.

dataset.h5ad 117.4 MiB
Download
s3://openproblems-data/resources/datasets/openproblems_v1/mouse_blood_olsson_labelled/log_cp10k/dataset.h5ad

Used in

References

  1. Olsson, A., Venkatasubramanian, M., Chaudhri, V. K., Aronow, B. J., Salomonis, N., Singh, H., & Grimes, H. L. (2016). Single-cell analysis of mixed-lineage states leading to a binary cell fate choice. Nature, 537(7622), 698–702. 10.1038/nature19348 ↗